Having done research on Cissus Quadrangularis for many years now we, at the Cissus Experts, felt it may be important to note that many herbs, including Cissus Quadrangularis, may have different common names throughout the world. Cissus, the genus name, is the most common name which stems from the species name Cissus Quadrangularis. In most studies you will find the name written as C. quadrangularis, CQ, CQE, or CQR-300.
Cissus is commonly known as Veldt Grape, Devil’s Backbone, or Winged Treebine.
Cissus in India
Cissus has a long history of medicinal use in India and is commonly referred to as Hadjod, translated as ‘(the one) that unites broken bones’ in Hindi, while its Sanskrit name, asthisamharaka, literally means ‘protecting bones from destruction’.
Cissus in Thailand
In Thai, Cissus is written เพชรสังฆาต, which transliterates to “Phet sang kat” or “Phet Sangkhat”. It is mostly prescribed to relieve hemorrhoids, which is one benefit due to it’s anti-inflammatory properties. Some Thais are learning more about the wide range of benefits of Cissus.
A list of what Cissus Quadrangularis can otherwise be known as:
Asthisonhara, Chadhuri, Chaudhari, Cissus, Cissus Extract, Cissus Formula, Cissus Formulation, C. Quadrangularis, Cissus Quadrangularis, Cissus Quadrangularis Extract, CORE, CQ, CQE, CQR-300, Extrait de Cissus, Hadjod, Hadjora, Harbhanga, Harsankari, Hasjora, Kandavela, Mangaroli, Nalleru, Namunungwa, Phet Cha Sung Khaat, Phet Sang Kat, Phet Sangkhat, Pirandai, Quadrangularis, Samroi To, San Cha Khuat, Stemmed Vine, Vajravalli, Vedhari, Veld Grape, Veldt-grape, Vitis quadrangularis, Winged Treebine.
The many therapeutic uses of Cissus is just staggering. The list just keeps on growing! Every time the Cissus experts think we have
heard of it all, we find more and more uses for Cissus quadrangularis. All these positive uses and we still haven’t found one negative study. In fact, Cissus was found to have no toxicity. Not too surprising since it is an anti-oxidant as well.
The stout, fleshy quadrangular stem is traditionally used for the treatment of: gastritis, bone fractures, skin infections, constipations, eye diseases, piles, anemia, asthma, irregular menstruation, burns and wounds.
Leaves and Shoots – Powerful Alteratives
The leaves and young shoots are powerful alteratives. (An alterative is a medicinal substance that acts gradually to nourish and improve the system.
Powder is administered in treatment of hemorrhoids and certain bowl infections.
The juice of stem is useful in scurvy and in irregular menstruation whereas the stem paste boiled in lime water is given in asthma.
It is also used as a powerful stomachic.
Cissus quadrangularis Linn. has potent fracture healing property and antimicrobial, antiulcer, antioxidative, antiosteoporotic, gastroprotective, cholinergic activity as well as beneficial effects on cardiovascular diseases.
It has been investigated that methanolic extract of Cissus quadrangularis possesses antiulcer and cytoprotective property in indomethacin induced gastric mucosal injury.
The aqueous extract also shows acetylcholine like activity on isolated ileum of rabbit and uterus of rat.
The action on dog blood pressure is analogous to muscarinic and nicotinic actions of acetylcholine.
Ethyl acetate fractions of both fresh and dry stem extracts show antioxidant activity.
The ethyl acetate extract and methanol extract of both fresh and dry stem further exhibit antimicrobial activity against gram-positive bacteria including Bacillus subtilis, Bacillus cereus, Staphylococcus aureus and Streptococcus species.
Due to its widespread and versatile therapeutic uses as well as pharmacological actions, the present study highlighted the health promoting and therapeutic properties of Cissus quadrangularis.
These therapeutic uses were documented in an official clinical study of Cissus called:
Pharmacological and Therapeutic Activity of Cissus quadrangularis: An Overview By Garima Mishra1*, Saurabh Srivastava2, B.P.Nagori3
From The International Journal of PharmTech Research
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Cissus Quadrangularis was originally written about in a Yoga text Ayurveda. It’s in the grape family, and we all know how the anti-oxidents of wine have be shown to protect the body. Well, Cissus is in the same family as the wine grape.
It’s more powerful and potent than most anti-oxidents found.
So why is Cissus Quadrangularis so hidden from the mainstream market?
Cissus only grows in a few places in the world and it has been marketed for many different uses, but none as popular as the Weight Loss and Weight Lifting communities.
It is grown in SouthEast Asia and India and it is even rare to find throughout these areas.
How did I stumble upon Cissus Quadrangularis?
Cissus in Thailand
While traveling through Southeast Asia, I ruptured my Achilles Tendon. Not a good injury to have while trekking around.
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Cissus quadrangularis is used for obesity, diabetes, a cluster of heart disease risk factors called “metabolic syndrome,” and high cholesterol. It has also been used for bone fractures, weak bones (osteoporosis), scurvy, cancer, upset stomach, hemorrhoids, peptic ulcer disease (PUD), painful menstrual periods, asthma, malaria, and pain. Cissus quadrangularis is also used in bodybuilding supplements as an alternative to anabolic steroids.
Cissus heals like Wolverine
Cissus can be found (more hidden) in many supplements and medications. Cissus can be taken as an extract or blended with other supplements. The list of benefits goes on and on as we discover more about this ancient medicinal herb.
Cissus Muscle Repair
Cissus is used by body builders to repair torn muscles, ligaments, and bones. It can be used by all athletes who suffer bone fractures or torn tendons such as ACL/MCL tears, Achilles tendon tears, or any joint/tendon injury.
Joint Health
Cissus is a natural joint health supplement similar to DHEA or MSM. Cissus allows for joint, tendon, and ligament repair.
Bone Support
A latest study shows that cissus directly helps bone marrow make the bone-building cells known as osteoblasts as well as directly promote the formation of calcium matrix (new bone)
Workout Recovery
Cissus can improve your workout recovery time and allow your body to gain maximum benefits from over strenuous exercise.
Cortisol Blocker
This is one of the main goals of body builders since cortisol, a natural hormone in our bodies, breaks down muscle when they are stressed. This means cortisol is working against heavy workouts. By blocking cortisol your body allows muscles to get ripped. Cortisol also plays a part in breaking down sugars and amino acids which can get stored as fats, another thing bodybuilders don’t want.
Weight Loss/Management
When we are stressed, either physically, mentally, or emotionally, our bodies send out hormones to defend itself. Cortisol is one hormone our bodies send out. What happens then is our body finds sugars to break down to store as fat in order to protect our cells from stress. Cissus prevents the cortisol from interfering with our muscle growth and prevents the fat build up.
Cissus Anti-Oxidant Properties
Cissus is in the grape family and therefore carries great anti-oxidant properties for the human body. This makes cissus healthy for everyone. Most of the diseases and problems that cissus can be used to aid come down to fighting oxidants in our bodies. Digestive problems are the root of most of our health problems and the main cause of poor digestion is all the oxidants our bodies are fighting everyday.
Gastroprotective Activity
Cissus has been used to treat hemorrhoids and other digestive aids such as ulcers, asthma, and constipation – all important issues that are associated with bacterial imbalance in the digestive tract.
Malaria
Cissus has been used by Africans, for centuries, to relieve symptoms of and prevent Malaria. The cissus plant contains anti-malaria agents that can subdue the effects of malaria.
Irregular Menstruation
Cissus promotes estrogenic activity, mostly in rats that are a research model for menopause. It has not been investigated as to whether this estrogenic activity influences male performance or sexuality, however.
Eye/Ear Disease
Cissus Quadrangularis carries high levels of carotene and antioxidants making it an aid in fighting most diseases, especially in the ears and eyes.
Anorexia
Cissus Promotes Overall Health
Anorexia is not just some teenager deciding to get thin by CHOOSING not to eat, but rather a disease that can be brought on by chemical imbalances within the body and/or by digestive problems.
Cissus quadrangularis contains a variety of phytonutrients such as quercetin, stillbenes, beta carotene, and other flavonoids. These nutrients help your digestive lining in several ways including preventing gastric damage, boosting antioxidant function, reducing inflammation, and preserving the capillary integrity and normal function of your stomach and digestive lining.
The weight loss effects of Cissus are not mainly appetite suppression, but rather the fact that by inhibiting cortisol you are also inhibiting the liver to process extra sugars that potentially can be stored as fat when the body is under stress. This in itself can prevent weight gain, but in a healthy way. Some people may feel their appetite suppressed a bit, but it’s mostly suppressed against over snacking and sugar cravings.
Cissus should be taken 30 minutes before eating, so the herbal supplements support eating. We probably tend to over eat at single meals anyway, so a natural appetite suppressant shouldn’t have any harm, even to someone anorexic.
Burns
Cissus can also be used as an external ointment on both bone fractures and skin burns. It’s anti-oxidant capabilities and over healing powers heal the skin also.
Asthma
Oxidants and Stress are two major causes of asthma. Cissus carries high levels of anti-oxidants and promotes a healthy chemical balance within the body. Although our only real cures for stress are lifestyle choices and changes, the effects of stress are chemical imbalances within the body which tend to negatively affect our digestion, our weight, and our mood. Cissus Quadrangularis has healing abilities in all these fields, especially in the digestive tract.