The Therapeutic Uses of Cissus Is Just Staggering!

The many therapeutic uses of Cissus is just staggering.  The list just keeps on growing! Every time the Cissus experts think we have
heard of it all, we find more and more uses for Cissus quadrangularis.  All these positive uses and we still haven’t found one negative study.  In fact, Cissus was found to have no toxicity.  Not too surprising since it is an anti-oxidant as well.


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The stout, fleshy quadrangular stem is traditionally used for the treatment of:  gastritis, bone fractures, skin infections, constipations, eye diseases, piles, anemia, asthma, irregular menstruation, burns and wounds.

Cissus Leaves and Shoots

Leaves and Shoots – Powerful Alteratives

The leaves and young shoots are powerful alteratives. (An alterative is a medicinal substance that acts gradually to nourish and improve the system.

Powder is administered in treatment of hemorrhoids and certain bowl infections.

The juice of stem is useful in scurvy and in irregular menstruation whereas the stem paste boiled in lime water is given in asthma.

It is also used as a powerful stomachic.

Cissus quadrangularis Linn. has potent fracture healing property and antimicrobial, antiulcer, antioxidative, antiosteoporotic, gastroprotective, cholinergic activity as well as beneficial effects on cardiovascular diseases.

It has been investigated that methanolic extract of Cissus quadrangularis possesses antiulcer and cytoprotective property in indomethacin induced gastric mucosal injury.

The aqueous extract also shows acetylcholine like activity on isolated ileum of rabbit and uterus of rat.

The action on dog blood pressure is analogous to muscarinic and nicotinic actions of acetylcholine.

Ethyl acetate fractions of both fresh and dry stem extracts show antioxidant activity.

The ethyl acetate extract and methanol extract of both fresh and dry stem further exhibit antimicrobial activity against gram-positive bacteria including Bacillus subtilis, Bacillus cereus, Staphylococcus aureus and Streptococcus species.

Due to its widespread and versatile therapeutic uses as well as pharmacological actions, the present study highlighted the health promoting and therapeutic properties of Cissus quadrangularis.

These therapeutic uses were documented in an official clinical study of Cissus called:
Pharmacological and Therapeutic Activity of Cissus quadrangularis: An Overview
By Garima Mishra1*, Saurabh Srivastava2, B.P.Nagori3

From The International Journal of PharmTech Research
Cissus is Therapeutic